The Church of Agioi Anargyroi is one of Chania's most significant spiritual and historical sanctuaries.

Located in the eastern part of the old town, in the picturesque district of the same name, its history is inextricably linked to the survival of the Christian element during the difficult centuries of Ottoman rule. Its construction dates back to the 16th century, during the Venetian period, and it originally served as the catholicon of a monastery.

The church's uniqueness lies in the fact that, after the city fell to the Ottomans in 1645, it remained the only Orthodox church permitted to operate within the city walls of Chania. This exceptional concession turned Agioi Anargyroi into the unofficial cathedral of the city for nearly two centuries (until 1860). For generations of Chanians, this church was not just a place of worship but a symbol of their religious and national identity—the beating heart of the Orthodox community in a city undergoing radical change.

Inside, the church maintains a solemn and evocative atmosphere reminiscent of Byzantine traditions. It houses an exceptionally rare collection of Byzantine and post-Byzantine icons, many of which were crafted by great hagiographers of the Cretan School. The wood-carved iconostasis and the old frescoes bear the marks of time and history, enhancing the site's unique historical aura. Even today, Agioi Anargyroi remains one of the residents' most beloved churches, serving as a silent witness to the resilience and continuity of Chania's traditions through the centuries.