Mesa Lasithi is a traditional village on the Lasithi Plateau serving as the main settlement and community seat in the region.

Situated at an elevation of around 850 meters, it offers beautiful views of the surrounding plains and mountains while retaining its traditional Cretan architectural charm. The village is surrounded by agricultural land and small paths connecting nearby communities such as Mesa Lasithaki, Nikiforidon, and Smalianon.

The settlement functions as a base for visitors to explore various religious sites in the area, including the Church of the Annunciation of the Virgin Mary and other chapels typical of the region.