Chamezi is a historic settlement in the Lasithi prefecture, built in the mountainous hinterland of eastern Crete along the main road axis connecting Sitia with Agios Nikolaos.

The village is widely known for its rich cultural heritage and its strategic position overlooking the rugged Cretan landscape.

The most noteworthy features to see in Chamezi include the Folklore Museum Hamezion, which preserves local traditions, and the Minoan Villa Hamezi, a significant archaeological site testifying to the long history of the area. Additionally, the proximity to traditional production units, such as the local olive oil factory, highlights the rural character of the region.

A tour of Chamezi reveals a place that maintains its authenticity while serving as a gateway for exploring neighboring settlements like Skopi. The settlement is traversed by the Northern Road Axis of Crete and European Route 75, making it easily accessible for travelers moving through eastern Crete, while offering a unique glimpse into life in the Lasithi countryside.